Based on the ceRNA network, we also discovered that FOS, IGF1R, IGF2, FOXO1, and NTF3 might target the “TGF-β signaling pathway”, “the hedgehog signaling pathway”, “retinol metabolism”, or “type II diabetes mellitus” pathways respectively, thereby modulating the subsequent development of ICC. The gene discussed is IGF2; the disease is intrahepatic cholangiocarcinoma.