Serum levels of sICAM-1 (p < 0.001), IL-1β (p < 0.001), MIF (p = 0.038), and su-PAR (p < 0.001) in patients with AE-IPF were significantly higher than those in patients with stable IPF (Figure 2). This evidence concerns the gene IL1B and idiopathic pulmonary fibrosis.