We also examined the ability of inosine to potentiate adoptive-transfer-based therapy, which transfers Pmel+ T cells to mice bearing B16-F10 xenografts (Fig. 6b) or GD2-CAR T cells to immune-deficient mice bearing GD2-positive human neuroblastoma (LAN-1) xenografts (Fig. 6c). Here, PMEL is linked to neuroblastoma.