The results of T test showed that serum concentration of IL-32 in patients with stable COPD (169.9 ± 51.9 pg/mL) was higher than that in healthy individuals (105.1 ± 43.3 pg/mL) (T = − 7.476, Df = 144, p < 0.001) (Fig. 1A; Table 1). The gene discussed is IL32; the disease is chronic obstructive pulmonary disease.