In line with this, in our study, Cav1 displayed low expression in IPF fibroblastic cell line (Fig. 4b), and the dual-luciferase reporter gene assay showed that the decline was due to the combination of miR-526b and 3′ UTR of Cav1, the overexpression of circTADA2A released Cav1 expression via sponging miR-526b. The gene discussed is CAV1; the disease is idiopathic pulmonary fibrosis.