These data are also relevant to the field of hepatocellular carcinoma, as we have found that different hepatoma cell lines derived from different tumor clones from three different animal species and that have been cultured for years, appear to converge toward similar derangements of PI3K-AKT and RAS-MAPK signaling, glucose metabolism, and protein expression profile. Here, AKT1 is linked to hepatocellular carcinoma.