SHC1 and Cognitive impairment: In our CNC network analysis, the expression of lncRNA NONMMUT113601.1 correlated positively to Shc1 expression and could regulate it in cis. LncRNA NONMMUT041306.2 and NONMMUT115748.1 could mediate gene expression by binding to the transcription factors C/EBPs in trans. These data suggested that these potential key lncRNAs in our study may regulate the corresponding target genes expression participating in the formation and development of cognitive impairment after CA/CPR.