Although ME/CFS patients with sr-IBS had decreased IgG1 (aOR = 0.361, p-value = 0.037) and increased IGHA2 (aOR = 2.852, p-value = 0.046) levels, these findings were not significant after adjustment for multiple testing. The gene discussed is IGHA2; the disease is myalgic encephalomeyelitis/chronic fatigue syndrome.