An online gene chip profile (GSE12639) indicated that a total of 753 genes are differentially-expressed in rats with streptozotocin (STZ)-induced diabetic MI, compared with nondiabetic rats with MI, and 18 genes a (log2|FC| > 0.56, p < 0.05), including γ-aminobutyric acid receptor, cholinergic receptor, urotensin receptor, endothelin receptor, adrenergic receptor β2 (ADRB2), melanocortin 5 receptor and oxytocin receptor were significantly different. Here, ADRB2 is linked to myocardial infarction.