TUNEL assay showed that apoptotic rate of H2O2-treated RA-FLSs was significantly higher compared to untreated controls and H2O2-treated Mst1-silenced RA-FLSs (Tunel-positive cells: 38% vs. 3% vs. 10%; Figure 1F–1G). Here, MST1 is linked to rheumatoid arthritis.