NLRP3 and idiopathic pulmonary fibrosis: NLRP3 inflammasome activation is implicated in the pathogenesis of IPF (Lasithiotaki et al., 2016) and contributes to the development of experimental lung fibrosis in aged mice, with bleomycin‐treated aged NLRP3−/− mice showing reduced lung fibrosis compared to their WT age‐matched counterparts (Stout‐Delgado et al., 2016).