KLK3 and neoplasm: Patients with DM were slightly older (68.6 ± 10.3 vs. 64.8 ± 8.3, p < 0.001), more frequently had a PSA level higher than 20 ng/ml (73.5 vs. 8.4%, p < 0.001), more frequently harbored biopsy GG 5 (57.5 vs. 7.4%, p < 0.001), had a higher proportion of positive cores > 2/3 (74.4 vs. 18.1%, p < 0.001) and more frequently harbored advanced and regional tumor stages (all p < 0.05) than those without DM.