In the 107 patients studied, we found p53, PD-L1, CA19-9, surgical time, operative procedure, venous invasion-positive, nerve invasion-positive, lymph node metastasis, and T factors to be significantly associated with poor prognosis; of these nine factors, six with the lowest P values (p53, PD-L1, CA19-9, operation time, operative procedure, and lymph node metastasis) underwent multivariate analysis. This evidence concerns the gene CD274 and metastatic malignant neoplasm in the lymph nodes.