EGFR and metastatic malignant neoplasm in the lymph nodes: As shown in Table 2, EGFR mutations were found more frequently in females (p = 0.011), those who had never smoked (p = 0.041), and those with less lymph node metastasis (p < 0.001), but no significant association was found with age (56 ± 6 vs 60 ± 8 years, p = 0.068).