IL17A and asthma: Pathway enrichment results of genes with eQTLs suggest that whereas IL-13 may be more of an inducer of immune processes, consistent with the T2 endotype that has a significant allergic component, IL-17A may be more of an inducer of structural changes in ASMCs and subsequent predisposition to AHR, possibly resulting in more refractory asthma, consistent with the Th17 endotype.