In line with recent work [15], we observed that CDK7 inhibitor THZ1 reduced phosphorylation of RNAPII CTD at S2, S5, and S7 sites in NSCLC cells, indicating effective inhibition of global transcription [7] which is confirmed by RNA-seq in THZ1-treated NSCLC cells. The gene discussed is CDK7; the disease is non-small cell lung carcinoma.