Factors associated with hypokalemia in univariable logistic regression include age, CVA, COPD, DM, HTN, CHF, CKD, diarrhea, potassium-sparing diuretics, thiazides, sulfonamides, beta-2-adrenoreceptor agonists, xanthines, steroids, and laxatives. This evidence concerns the gene ADRB2 and chronic obstructive pulmonary disease.