IL33 and atopic eczema: TSLP and IL33 both play a role in the induction of atopic dermatitis-like skin lesions following topical application of the vitamin D analogue calcipotriol [76, 77], and overexpression of TSLP and IL33 in the epidermis of transgenic mice induced a type 2 inflammatory response with accumulation of mast cells, eosinophils, and an increase of serum IgE [78, 79].