PDIA3 expression was positively correlated with HCK, LCK, MHC-I, MHC-II, STAT1, and interferon, but negatively related to IgG in pan-glioma (Figure 8A, 8B) and GBM (Supplementary Figure 8) analysis based on both TCGA and CGGA datasets. Here, PDIA3 is linked to central nervous system cancer.