These results indicate the potential tumor-promoting features of monocytes in NPC,33 consistent with their high expression of S100A8 and S100A9 (Fig. 3c).34 We then applied Single-Cell Regulatory Network Inference And Clustering (SCENIC) analysis35 to correlate transcription factors (TFs) with gene expression differences among cell types. The gene discussed is S100A9; the disease is nasopharyngeal carcinoma.