Likewise, although NMT1 genetic targeting recapitulated most of the effects of NMTi treatment in lysosomal function, and we did not observe increased NMT2 expression in cells with reduced levels of NMT1, we cannot rule out that NMT2 plays a role in LAMTOR1 myristoylation, or lysosomal functions in cancer cells. Here, NMT1 is linked to cancer.