TP53 and colorectal carcinoma: Among individuals with a somatic mutation in TP53, those with 0% predicted residual TP53 activity had significantly poorer CRC-specific survival compared to those with mutations causing >5% predicted residual activity or those with no mutations (HR = 1.53, 95% CI: 1.21–1.94) after adjusting for age, sex, mutational burden, and study.