TFs that were positively regulated by the immune gene VIPR1 included EPAS1, TCF21 and CBX7. Studies have shown that the TF ETV1 [23] increases the risk for carcinogenesis by increasing NSCLC proliferation; furthermore, it is negatively correlated with overall survival in patients with NSCLC. The gene discussed is TF; the disease is non-small cell lung carcinoma.