Even though epigenetic regulation of PRC1 expression in human cancers has not been reported, overexpression of PRC1 has been described in many cancers, such as urothelial carcinoma of the urinary bladder (Su et al. 2019) and adenocarcinoma of the colon (Subramaniyan et al. 2016). This evidence concerns the gene PRC1 and bladder transitional cell carcinoma.