Melatonin receptors MTNR1A and MTNR1B SNPs have been linked to autoimmune diseases, including Graves' disease in a study on 83 Hashimoto's thyroiditis showing variations of rs2119882 of MTNR1A supporting melatonin pathway involvement in Graves' disease pathogenesis [14]. The gene discussed is MTNR1B; the disease is Graves disease.