This study was conducted to compare the cost-effectiveness of a simple insulin infusion device to MDI for individuals with T2D not in glycemic control on MDI, where effectiveness data were obtained from the OpT2mise trial.11 The results indicate a simple insulin infusion device will be highly cost-effective in the United States at a price of around $13 per day and remain cost-effective up to a price of around $17 for people with T2D. Here, INS is linked to type 2 diabetes mellitus.