Moreover, circPIP5K1A [34], circMAN2B2 [35], circNRIP1 [36], and circNF1 [37] are all upregulated in GC samples and promote GC progression through the miR-671-5p-KRT80-PI3K/AKT, miR-145-PI3K/AKT/JNK, miR-149-5p-AKT/mTOR, and miR-16-AKT axes, respectively. The gene discussed is MTOR; the disease is gastric cancer.