Belinsky et al. reported the methylation detection of 8 selected genes (CDKN2, MGMT, DAPK1, RASSF1, GATA4, GATA5, PAX5α and PAX5β) in sputum and blood had prognostic value for recurrence in stage IA (pT1N0) or stage IB (pT2N0) NSCLC 24. This evidence concerns the gene MGMT and non-small cell lung carcinoma.