CTNNB1 and neoplasm: The results of the apoptosis assay revealed that MYH9 knockdown (MYH9 shRNA3 + vector) increased tumor cell apoptosis when compared with the control group (NC + vector), while MYH9 or CTNNB1 overexpression (MYH9 shRNA3 + MYH9 or MYH9 shRNA3 + CTNNB1) rescued tumor cell apoptosis (Figure 6C, S19A and S19C), suggesting that MYH9 knockdown-induced cell apoptosis is associated with a reduction of CTNNB1 expression.