MYC and hepatocellular carcinoma: In addition, immunofluorescence coupled with RNA FISH assay was performed to localize and quantify the expression of lncCSMD1 and MYC protein in the primary HCC tissues (n=11), and the result indicates that both lncCSMD1 RNA and MYC protein are located in the nuclei of HCC cells and have a close and positive relationship (Figure 7D and Figure S9).