For example, the lncRNA DANCR and UFC1 activate Wnt signaling via stabilizing CTNNB1 protein 17, 18; lncRNA Ptn-dt promotes the proliferation of HCC cells by interacting with HuR protein 19; linc-GALH promotes metastasis of HCC through controlling the methylation status of Gankyrin by adjusting the ubiquitination status of DNMT1 20. The gene discussed is DNMT1; the disease is hepatocellular carcinoma.