Not unexpected, the results indicate that the lncCSMD1 overexpression cannot rescue the inhibition of cell proliferation (Figure 7A), colony formation (Figure 7B) and invasion (Figure 7C) of the HCC cells induced by knockdown of MYC compared with the control cells, and lncCSMD1 downregulation also cannot further inhibit cell proliferation, colony formation and invasion of HCC cells with MYC knockdown (Figure S8) compared with the control cells. The gene discussed is MYC; the disease is hepatocellular carcinoma.