TMEM11 and hearing loss disorder: According to the American College of Medical Genetics and Genomics/Association for Molecular Pathology guidelines for genetic hearing loss [26, 27], c.696G>T (p.Glu232Asp) is classified as a likely pathogenic variant (PM1+PM2+PM5+PP1+PP3), c.325C>T (p.His109Tyr) is classified as a variant of uncertain significance (PP1), c.635T>C (p.Leu212Pro) is classified as a likely pathogenic variant (PM1+PM2+PP1+PP3), whereas c.183delG (p. Ala62Argfs∗22) is classified as a pathogenic variant (PVS1+PM2+ PP1) (Table 1).