Similar to that observed in TRPM7i cells (Fig. 3c, d), an inhibition of OGT effectively decreased cell migration as compared to control (Fig. 3e, f and Supplementary Fig. S6), thus confirming the promoting role of hyper-O-GlcNAcylation in NSCLC motility. The gene discussed is OGT; the disease is non-small cell lung carcinoma.