TRPM7 and non-small cell lung carcinoma: To determine further the causal relationship between TRPM7 function and lung carcinoma cell motility, NSCLC NCI-H292 and NCI-H460 cells were incubated with various concentrations of a non-specific inhibitor of TRPM7, 2-APB, and its effects on Ca2+ influx, cell migration and invasion were evaluated.