SOCS1 and neoplasm: Analyses of the TCGA data retrieved from cBioPortal revealed a positive correlation between the expression of BAP1 and that of FOXK1/K2 direct target genes in a panel of human cancer cell lines, including VHL and SOCS1/2 (Fig. S8), supporting these tumor suppressor genes are downstream targets of the BAP1-containing PR-DUB complex.