Interestingly, in our KEGG pathway analysis the only category that emerged was HD in the comparison between AAV-LAV-BPIFB4- and AAV-GFP-treated mice, while between AAV-LAV- and AAV-WT-BPIFB4 the highest score has been reached by cAMP signaling pathway (Fig. 6). The gene discussed is BPIFB4; the disease is Huntington disease.