ESR1 and coronary artery disorder: For ESR1 gene SNPs, the haplotype C-G was found to confer approximately 5-fold risk [OR = 4.906 (3.604–6.678), p = 5.00e-015] and T-A about 1.6 fold risk [OR = 1.616 (1.318–1.980), p = 3.61e-006] of CAD outcome in the studied population.