Older age (>65), presence of comorbidity (especially coronary artery disease and chronic obstructive pulmonary disease), bilateral ground-glass opacity and patchy infiltration on CT, low lymphocyte count, high neutrophil/lymphocyte ratio, low monocyte count, low platelet count, elevated liver enzymes, low GFR, high levels of muscle enzymes, and high levels of ferritin and IL-6 on admission are predictors of SARI and severe disease. The gene discussed is IL6; the disease is chronic obstructive pulmonary disease.