Given that miR-31 was shown to target ARID1A to further transactivate EpCAM and subseqently enhance the oncogenicity and stemness of head and neck squamous cell carcinoma [33], it is highly possible that miR-31 is the mediator for the TINCR-regulated EpCAM, reported by Zhang et al. [21]. The gene discussed is EPCAM; the disease is head and neck squamous cell carcinoma.