Genotyping of PDE8B rs6885099 polymorphism wascarried out in 60 IF-SCH and 76 control females (Fig .2B).The observed genotype frequencies of PDE8B rs6885099polymorphism among the control and IF-SCH femaleswere in accordance with HWE (P=0.248 and P=0.134respectively; Table 2). This evidence concerns the gene PDE8B and spindle cell hemangioma.