For example, MYC expression in the activation of lymphocytes [26] or in Burkitt’s lymphoma [27] is associated with a universal amplification of transcription, while we observed that in LNCaP PCa cells with up-regulated MYC, knocking down MYC by <50% with shRNA consistently increased the total amount of RNA produced per cell. This evidence concerns the gene MYC and posterior cortical atrophy.