The 8q24 region has been linked with numerous cancer types, however the locus harbors only a few protein-coding genes such as FAM80B and the proto-oncogene MYC but, several lncRNA genes including, PCAT1, PCAT2, PRNCR1, CCAT1, CCAT2, CASC19, CASC21, and PVT1. Except for CASC19 and 21, all other lncRNAs have been linked to various cancers9–16. This evidence concerns the gene PVT1 and cancer.