ITGAX and lobular neoplasia: In the present study, we report the significance of CD11c+ macrophages, whose urinary levels showed significant differences according to LN classification (proliferative LN vs. non-proliferative LN), anti-dsDNA antibody titer, and clinicopathologic features of proliferative LN such as chronicity (e.g., tubular atrophy, interstitial fibrosis, and renal response).