In CBA studies, serum IL-4 (9.743 ± 0.7713 versus 6.594 ± 0.2539, P = 0.0013) and IL-6 (44.10 ± 8.109 versus 11.57 ± 1.937, P = 0.0017) levels were significantly higher in patients with DM-ILD than healthy controls. This evidence concerns the gene IL4 and interstitial lung disease.