Moreover, In DM patients, the levels of IL-4, IL-6 and S100A8/A9 were significantly higher in patients with A/SIP than in those with CIP (p = 0.0046, 0.0339 and 0.0133) or without ILD (p = 0.0165, 0.0370 and < 0.0001) (Fig. 1). This evidence concerns the gene S100A8 and hereditary sensory and autonomic neuropathy.