A third unexpected morphology of large, dysplastic ganglion-like cells (GCs), as in ganglioglioma, previously reported in DMG/K27M [29], with H3-K27M expression but lacking BRAF mutations, was present in F10 pons focally (Fig. 2, panels 11–12, Suppl. Fig. S4), demonstrating the metaplastic potential of these neoplastic cells. The gene discussed is BRAF; the disease is ganglioglioma.