NFKBIB and schizophrenia: We found a main effect of inflammation on IκBα and IκBβ transcripts in the human PFC, where IκBα and IκBβ were increased in high vs. low neuroinflammatory status (IκBα F(1,127) = 86.012, p < 0.0001, IκBβ F(1,137) = 11.671, p < 0.0001) to a greater extent in controls than in schizophrenia (Fig. 4).