For RelB transcript, we found a main effect of diagnosis, where people with schizophrenia had decreased RelB mRNA overall, with (F(1,127) = 6.306, p = 0.013, − 17%) or without (t(118) = 2.496, p = 0.014, − 16%) the inclusion of high neuroinflammation controls (Fig. 5). This evidence concerns the gene RELB and schizophrenia.