The Hb values in the three probands was examined and severe anemia was indicated in the infants (Family 1 III1, 89 g/L; Family 2 II2, 54 g/L; Family 3 II1, 99 g/L), and the mothers of the infants in the three probands (Family 1 II2, 93 g/L; Family 2 I2, 109 g/L; Family 3 I2, 95 g/L). This evidence concerns the gene GSTM1 and anemia (phenotype).