Because only a small number of subjects were homozygous rs2920656 (n = 26), we also tested associations between rs2920656 and AKI-SP2 in a dominant genetic model, which gave consistent results (OR, 0.42; 95% CI, 0.28–0.64; p < 1.4 × 10− 6). This evidence concerns the gene SP2 and acute kidney injury.