We also evaluated the serum and hNEX p-tau (T181)/Aβ1-42 ratio level, but found no significant differences among groups (serum: AMC, 0.44 ± 0.04; MCI, 0.37 ± 0.02; Mild-AD, 0.52 ± 0.06, Figure S4C; hNEX: AMC, 4.70 ± 0.64; MCI, 4.37 ± 0.40; Mild-AD, 3.62 ± 0.43, Figure S4F). Here, MAPT is linked to Alzheimer disease.