In addition, the hNEX p-tau (S202)/t-tau ratio was significantly higher in the MCI compared to the AMC group (AMC, 0.37 ± 0.03; MCI, 0.45 ± 0.036; Mild-AD, 0.34 ± 0.01, p < 0.05 vs. MCI, Figure 2D). The gene discussed is MAPT; the disease is Alzheimer disease.