The Mild-AD group also demonstrated a significantly higher hNEX p-tau (S202, T205)/t-tau ratio than the MCI group (AMC, 1.00 ± 0.06; MCI, 0.84 ± 0.06; Mild-AD, 1.30 ± 0.15, p < 0.01 vs. MCI, Figure S7G) and a higher hNEX p-tau (T181)/t-tau ratio than the AMC group (AMC, 1.00 ± 0.11; MCI, 1.47 ± 0.16; Mild-AD, 2.07 ± 0.32, p < 0.01 vs. AMC, Figure S7H). Here, MAPT is linked to Alzheimer disease.