There were no significant differences in p-tau (T181) among groups (serum: AMC, 9.59 ± 0.40; MCI, 9.68 ± 0.39; Mild-AD, 9.86 ± 0.69, Figure S4A; hNEX: AMC, 14.11 ± 2.68; MCI, 14.06 ± 3.04; Mild-AD, 22.05 ± 4.04, Figure S4D). This evidence concerns the gene MAPT and Alzheimer disease.