SNCA and Parkinson disease: The role of miR-30e in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced PD mouse model was examined, concluding that it downscales the neuroinflammation by lowering the activity of the NLRP3 protein, besides, an attenuation in the loss of dopaminergic neurons was described in the pars compacta of the substantia nigra (SNpc), accompanied by a reduction in the expression of the α-synuclein [64].