Dantham et al. [113] identified six dysregulated microRNAs associated with FRDA, where has-mir-15a-5p and hsa-mir-26a-5p target the BDNF gene; hsa-mir-29a-3p, hsa-mir-23-3p and hsa-mir-223-3p target the Glucose-6-phosphate Translocase (G6PT) gene; hsa-mir-24-3p could regulate the Dihydrofolate Reductase (DHFR) gene and hsa-mir-21-5p could feasibly negatively regulate a fundamental regulator—peroxisome proliferator-activated receptor α. This evidence concerns the gene DHFR and Friedreich ataxia.