Although the ch11q24.3 gain is not associated with the ABC phenotype when DLBCL are split in the two main subtypes, an enrichment for ch11q24.3 gains can be seen in the recently described DLBCL cluster 5, mainly comprising ABC-DLBCL, and cluster 2, driven by TP53 inactivation [4]. Here, TP53 is linked to diffuse large B-cell lymphoma.