INPP5D and carcinoma: These findings prompted us to investigate a putative role of the hematopoietic inositol 5-phosphatase SHIP1 in carcinomas, which shows endogenous expression only in the hematopoietic lineage and therein functions as a negative regulator of hematopoiesis and a suppressor of leukemogenesis [7,8,9,10,11,12,13].